Nefiracetam, also known as Cebrotonin and Lucetam, is an experimental nootropic. It has shown to enhance cognitive function and memory formation in animal studies, and is sometimes used in the treatment of Alzheimer's disease, senile dementia, and cerebral stroke. Nefiracetam has also been shown to protect the brain from damage after a traumatic brain injury and to enhance the efficacy of choline supplements.

Nefiracetam is a cholinergic and may increase the release of acetylcholine in the brain. In animal studies, it has been shown to increase brain levels of both choline and acetylcholine, and to increase the activity of choline acetyl transferase, the enzyme that converts choline to acetylcholine.

Nefiracetam has also been shown to increase levels of noradrenaline, dopamine, and serotonin in the brain. It has been suggested that nefiracetam may enhance cognitive function by increasing the release of these neurotransmitters.