TB-500 is a synthetic peptide that has been shown to have potent wound healing effects in a rat full-thickness wound model. Wounds treated with TB-500 showed a decrease in gap size and more wound contraction compared to control wounds.

TB-500 is a synthetic peptide that was originally developed for veterinary purposes. It is claimed to offer various therapeutic benefits, including the promotion of angiogenesis (formation of new blood vessels) in dermal tissues.

TB-500 up-regulates the action of actin, which promotes cell migration and proliferation. It also has been shown to promote angiogenesis, likely through the Notch signaling pathway.